Molecular Analysis of B Lymphocyte Development and Activation
K. L. Medina, H. Singh (auth.), Professor Dr. Harinder Singh, Professor Dr. Rudolf Grosschedl (eds.)The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. In the past five years, major advances have been achieved in our understanding of the transcriptional control of early B cell development and terminal plasma cell differentiation. In addition new insights became available for the processes of B cell activation, class switch recombination and somatic hypermutation. Many of the new findings and their implications for a molecular understanding of B cell biology in particular and cell differentiation in general are covered in this volume.
カテゴリー:
年:
2005
版:
1
出版社:
Springer-Verlag Berlin Heidelberg
言語:
english
ページ:
260
ISBN 10:
3540263632
ISBN 13:
9783540263630
シリーズ:
Current Topics in Microbiology and Immunology 290
ファイル:
PDF, 2.08 MB
IPFS:
,
english, 2005
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